Networking with the 1+ Million Genomes initiative

On December 15th, we had the pleasure of attending a meeting hosted by Szymon Bielecki (EC DG CONNECT - Unit H3: eHealth, well-being and ageing) with the cluster of EU-funded projects on the topic of AI for Genomics and Personalised Medicine - PANCAIM, INTERVENE and KATY on the 1+ Million Genomes initiative, which brings together 22 European countries, the UK and Norway with the goal of making at least 1 million sequenced genomes accessible in the EU by 2022.

This was a great opportunity to directly interact and discuss ethics and legal concerns (mainly on data sharing) with representatives from the B1MG (Beyond 1 Million Genomes) and their working group on Ethical, Legal and Social Issues (ELSI).

Check out their work here and stay tuned for more updates on this collaboration!

 

 

Photo by Warren Umoh on Unsplash

First joint meeting on Oxygenscan protocol harmonization

Earlier this month, GenoMed4All partners and collaborators met to discuss opportunities in OxygenScan protocol harmonization. The Oxygenscan test is particularly relevant for our use case group working on Sickle Cell Disease (SCD), as it measures the relative oxygen pressure at the precise moment red blood cells reach the Point of Sickling (PoS) and thus, describes the defined loss of deformability of red blood cells affected by SCD.

This first meeting was co-chaired by Mar Mañú and Amira Idrizovic from Vall d'Hebron Institute of Research and Minke Rab and Richard van Wijk from UMC Utrecht, and gathered experts from Università  degli Studi di Padova, APHP and additional interested parties from the Hematology department (Laboratory LHUB-ULB) at Erasme Hospital, Brussels.

The focus was on the standardization of key points in the OxygenScan analysis process within GenoMed4All's practice. Among the critical aspects that need to be considered are: hardware and software settings and machine set-up (e.g. fixed gain and oxygenation for the experiments), blood volume used for the test on red blood cell count, storage temperature for these blood samples, considerations of osmolarity for PVP vials, the pO2 spot.... Participants also agreed on a common methodology to check reproducibility of all experiments.

This is a meaningful first step in setting a baseline for the overall standardization of Oxygenscan tests, which will ultimately shape a compendium of best practices to share with future associate members of GenoMed4All within ERN-EuroBloodNet's member network.

 

 

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General Assembly #1 - the work so far

This week we celebrated our 6-month milestone with a General Assembly to reflect on the work done and all the challenges ahead.

As part of the meeting agenda, there were some breakout sessions planned to share the progress made on our use cases (both from the clinical and technical perspectives), discuss how to approach data sharing, ethics and GDPR and start working on our outreach and engagement strategy.

 

 

Photo by Austris Augusts on Unsplash

GenoMed4All's first official slide deck is now available

We are proud to share with you our first slide deck for GenoMed4All: a brief presentation on the scope and key figures of our project, and the best way to learn more about who we are, why we have embarked on this journey and what exactly we are working towards.

What you will find:

  • Our mission - Genomics for Next Generation Healthcare
  • Our ambition - Unleashing the power of AI
  • Our principles - An open source hub for Haematological Diseases
  • Our challenges - The context for Haematological Diseases
  • Our approach - New advanced models for genomics in precision medicine
  • Our team - 23 partners and the endorsement from EuroBloodNet, the European Reference Network in Rare Haematological Diseases

Take a look here!

 

 

Photo by Alex Litvin on Unsplash

Our public repository at Zenodo is live!

In GenoMed4All, we share the vision of the European Open Science Cloud and Open Access research initiatives. We are committed to making our results easily accessible to other fellow researchers and the wider community, and will provide open access to peer-reviewed publications and scientific data generated within our project.

That’s why we have set up a dedicated community and repository for GenoMed4All at Zenodo, where we will be uploading publications, public deliverables, data, press releases and more as the project goes on.

Check it out here


GenoMed4All begins its journey to bring Genomics to Next Generation Healthcare

GenoMed4All has officially launched!

This January, all 23 partners met online to kick-off this ambitious H2020 initiative. We are committed to push the limits on precision medicine in Haematological Diseases through Artificial Intelligence.

Here’s to a great 4-year run!

See our full press release here

 

 

Photo by Markus Winkler on Unsplash